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1.Show HN: We moved our Phase III 12.1 nautical miles offshore (yikescombinator.com)
847 points by mv_consent 3 hours ago | 214 comments
2.Do Things That Don't Scale Ethically (yikescombinator.com)
612 points by pgault 5 hours ago | 301 comments
3.Fett (YC S22) is hiring a Head of Sibling Relations (yikescombinator.com)
6 hours ago
4.Ask HN: Is it a pivot if the FDA makes you?
433 points by formerly_ingestible 7 hours ago | 96 comments
5.Insurable interest considered harmful (kindling.blog)
389 points by barnaby_k 8 hours ago | 178 comments
6.I was in distribution for 400 days straight. Then I skipped. (greenlight.substack.com)
356 points by four_hundred_green 9 hours ago | 142 comments
7.Golden Goose Biologics raises $80M Series B to "unlock the human gut as manufacturing capacity" (termsheet.news)
298 points by downstream_dan 10 hours ago | 167 comments
8.Launch HN: Scapegoat (YC W25) – Fractional Chief Accountability Officers (yikescombinator.com)
274 points by philippa_ad 11 hours ago | 88 comments
9.Buryn Hot reports 100% churn, 94 NPS (burynhot.com)
263 points by ltv_is_literal 12 hours ago | 412 comments
10.We rewrote our consent forms in Rust (oceania.engineering)
241 points by rustacean_42 13 hours ago | 203 comments
11.Why I left Pound (medium.com)
229 points by one_kidney_wiser 14 hours ago | 131 comments
12.United States v. [Sealed] (YC S23) [pdf] (justice.gov)
217 points by pacer_watcher 15 hours ago | 74 comments
13.Tell HN: Your cofounder can be compelled to testify. Your spouse can't.
204 points by second_time_defendant 16 hours ago | 119 comments
14.Lastly (YC W24): Our cohort retention curves look strange after year 40 (lastly.app)
188 points by evander_sc 17 hours ago | 93 comments
15.Ask HN: Who is being deposed? (October 2026)
176 points by whoisdeposed 18 hours ago | 257 comments
16.The unreasonable effectiveness of arbitration clauses (gault.essays)
171 points by clause_22 19 hours ago | 66 comments
17.Pinatubo (YC S25) accidentally cools Tulsa by 0.4°C, invoices city (tulsa-dispatch.com)
166 points by stratosfear 20 hours ago | 184 comments
18.Griftularity conductor billed 4,000 times to free a model that hasn't left (402media.co)
159 points by station_master 21 hours ago | 140 comments
19.Show HN: A browser extension that accepts all terms of service on behalf of your users (github.com)
148 points by i_agree_js 22 hours ago | 57 comments
20.TooBig (YC W23) rescued for third time; founders "humbled, again" (theledger.news)
141 points by moral_hazard_pay 23 hours ago | 99 comments
21.Golden Goose Biologics (YC W23) is hiring Downstream Processing Associates (yikescombinator.com)
1 day ago
22.Indenture (YC W24) opens secondary market for toddlers' upside (marketwire.news)
133 points by pro_rata_sibling 1 day ago | 171 comments
23.Resist (YC S24): Why we stopped A/B testing against placebo (resist.health)
127 points by colistin_and_chill 1 day ago | 88 comments
24.A SAFE, but the E stands for Exoneration (yikescombinator.com)
120 points by pgault 1 day ago | 45 comments
25.Limited Liability Is All You Need [pdf] (arxiv.org)
116 points by bayes_or_bust 1 day ago | 39 comments
26.Indulgent (YC S24) API outage leaves 40,000 transactions unabsolved (status.indulgent.dev)
109 points by mea_culpa_503 1 day ago | 62 comments
27.Ask HN: How do you handle on-call when the page is a subpoena?
98 points by sre_in_discovery 2 days ago | 51 comments
28.Delaware considered beneficial (gault.essays)
91 points by clause_22 2 days ago | 33 comments
29.Postmortem: our postmortem was subpoenaed (blameless.dev)
84 points by sre_in_discovery 2 days ago | 70 comments
30.Requests for Hazards: Winter 2027 (yikescombinator.com)
77 points by pgault 2 days ago | 124 comments
More results withheld pending discovery.